The University Court of the University of Edinburgh;Moredun Research Institute;SRUC
发明人:
David Gally,Tom Nathan McNeilly,David George Emslie Smith,Chris Low,Arvind Kumar Mahajan,Stuart W. Naylor
申请号:
US14949291
公开号:
US10363297B2
申请日:
2015.11.23
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Immunogenic compositions containing Escherichia coli 0157:H7 flagella including fusion proteins and methods using the immunogenic compositions are disclosed. Inducing an immune response in an animal to Escherichia coli O157:H7 flagella will result in prevention of colonization by Escherichia coli O157:H7 in the animal or a reduction in the amount of Escherichia coli O157:H7 infecting the animal. The immune composition will prevent or reduce the attachment of Escherichia coli 0157:H7 to cells within the animal.