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FAST DISINTEGRATING SOLID DOSAGE FORM FORMULATION COMPRISING FUNCTIONALIZED CALCIUM CARBONATE AND METHOD OF THEIR MANUFACTURE
专利权人:
发明人:
GERARD DANIEL E,SCHOELKOPF JOACHIM,GANE PATRICK A C,STRINIMANN TANJA,ALLES RAINER,PUCHKOV MAXIM,HUWYLER JÖRG
申请号:
IN638/MUMNP/2015
公开号:
IN2015MN00638A
申请日:
2015.03.24
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
An orally fast disintegrating dosage forms comprising functionalized natural or synthetic calcium carbonate at least one active ingredient and at least one disintegrant wherein said functionalized natural or synthetic calcium carbonate is a reaction product of natural or synthetic calcium carbonate with carbon dioxide and one or more acids wherein the carbon dioxide is formed in situ by the acid treatment and/or is supplied from an external source and wherein the tablet dissolves in less than 20 seconds when introduced into an aqueous environment.
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