PROCEDES DE TRAITEMENT DU TTP AVEC DES DOMAINES VARIABLES UNIQUES D'IMMUNOGLOBULINE ET UTILISATIONS ASSOCIEES

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专利权人:

ABLYNX NV

发明人:

DUBY, CHRISTIAN

申请号：

CA2952103

公开号：

CA2952103A1

申请日:

2015.06.16

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

The present invention is based on the finding that administration of polypeptides comprising at least one Immunoglobulin single variable domains against vWF to human TTP patients provides a significant decrease in the time to response. The invention provides a polypeptide comprising at least one immunoglobulin single variable domain (ISVD) against von Willebrand Factor (vWF) for use in treating a vWF-related disease in a human in need thereof. The invention further relates to dosage unit forms, kits and medical uses for treating TTP.

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