The present invention relates to a compound for use in lowering cholesterol, wherein the compound is selected from the group consisting of: DHAP； 1-acyl-DHAP； 1-alkyl-DHAP； 1-alkyl-G3P； 1-alkyl, 2-acyl-G3P； 1-alkyl, 2-acyl-glycerol； 1-alkyl, 2-acyl-GPE； I-alkyl, diacyl glycerol wherein sn-1=16:0, sn-2=DHA, sn-3=DHA, the sn-1 position has an alkyl ether bond, and the sn-2 and sn-3 positions have acyl bonds； 1-alkyl diacyl glycerol wherein sn-1=16:0, sn-2=18:1, sn-3=18:1, the sn-1 position has an alkyl ether bond, and the sn-2 and sn-3 positions have acyl bonds； triacyl glycerol wherein sn-1=16:0, sn-2=DHA, sn-3=DHA, and the sn-1, sn-2 and sn-3 positions have acyl bonds； and triacyl glycerol wherein sn-1=16:0, sn-2=18:1, sn-3=18:1, and the sn-1, sn-2 and sn-3 positions have acyl bonds； and pharmaceutically acceptable salts thereof.
