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NON-INVASIVE MARKER OF CELL PROLIFERATION/DIFFERENTIATION IN CELLS USING PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
专利权人:
INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
MUN, CHI WOONG,JANG, MOO YOUNG,CHUN, SONG I,KANG, BOK MAN,KWAK, SO YOUNG
申请号:
KR20120083135
公开号:
KR101333665(B1)
申请日:
2012.07.30
申请国别(地区):
韩国
年份:
2013
代理人:
摘要:

The present invention relates to non-invasive measurement for a cell signal, and a method thereof and, more particularly, to a measuring method which checks the proliferation and differentiation states of a cell using magnetic resonance spectroscopy and objectively evaluates the state of the cell by enabling the reuse of the cell. The purpose of the present invention is to provide a bio marker capable of checking proliferation and differentiation information of each cell, is to provide a measuring method capable of reusing the cell by non-invasively measuring a cell signal using magnetic resonance spectroscopy (MRS) which is a non-invasive device, and to provide an effect of significantly shortening costs and time used for one experiment. [Reference numerals] (a,e) Cytology specimen;(b) Magnetic spectra signal data;(c) Data normalization;(d) Differentiation marker decision;(f) Metabolome magnetic spectra data;(g) Cell differentiation condition determination

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