PETER KRESTEN NIELSEN,FRANTISEK HUBALEK,SVEND LUDVIGSEN,INGER LAUTRUP-LARSEN,ULLA RIBEL-MADSEN,PER BALSCHMIDT,PER NO̸RGAARD,SVEND HAVELUND
申请号：
PT07820423
公开号：
PT2074141T
申请日:
2007.09.20
申请国别(地区):
PT
年份:
2016
代理人:
摘要：
The present invention relates to novel insulin analogues exhibiting resistance towards protease, wherein at least two amino acids are substituted and/or deleted relative to the parent insulin molecule. A method for the preparation of such insulin analogues, insulin preparations containing the insulin analogues of the invention and a method of treating diabetes mellitus using these insulin analogues is also provided.
