Ludvigsen, Svend,Balschmidt, Per,Nielsen, Peter Kresten,Havelund, Svend,Lautrup-Larsen, Inger,Norgaard, Per,Hubalek, Frantisek,Ribel-Madsen, Ulla
申请号:
AU2007298919
公开号:
AU2007298919C1
申请日:
2007.09.20
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to novel insulin analogues exhibiting resistance towards protease, wherein at least two amino acids are substituted and/or deleted relative to the parent insulin molecule. A method for the preparation of such insulin analogues, insulin preparations containing the insulin analogues of the invention and a method of treating diabetes mellitus using these insulin analogues is also provided.