a. Drug compounds and compounds that can regulate the activity of quinase, including quinase and compounds of PI3 activity, drug components, disease treatment methods and conditions related to quinase activity, including quinase of PI3 activity. 1. Claim 1: a formula compound (1),Or an enantiomer, a mixture of enantiomers, or a mixture of two or more enantiomers, or a pharmaceutically acceptable form of enantiomers, w74951 and w74955, respectively； orS. O, n or nr.8308；At least one of w7495j1and w7495j2 is cr8310c,N or NR¹⁴；Wᵇ⁵ is CR⁸,P is 0, 1, 2 or 3； B is hydrogen, tar, beryllium, asphalt, amine, isotar, cyclopentyl compound, isocyclopropene, arilo or isopropene, each of which is replaced by 0-4r 2；2. Each R2 is an independent asphalt, isotar, sulphurous acid, asphalt, cyclopentyl, isocyclohexane, arilo, arilalquilo, isopropene, isopropenyl, alcox, amido, amino, acilo, aciloxi, alcoxibonilo, sulfuric acid, halo, cyanogen, hydroxyl, nitrite, phosphate, urea or carbonate； X does not exist or is - (CH (r8313)) 7611 -；He's not here, or- yes.-S (=O)-S (3DO) --N (R) --C (3DO) - (CHR) --C (=O)-N (R) -C (3DO) --N (R) -C (3DO) NH--N (R) C (R) --C (3DO) -N (R) o -C (3DO) -N (R) - (CHR) -Z is the integer 1, 2, 3 or 4； R 3 is the tar of c832283331；fluoro, bromo, iodo, cycloalkyl, cycloalkylalkyl, aryl, heteroaryl, heterocyclyl, aralkyl, heteroaralkyl, heterocyclylalkyl, alkenyl or alkynyl or R³ is a heteroatom selected from N, S and O, where the heteroatom has a covalent bond, either directly or through a C₁₋₆ alkyl group,1. Arilo, heterocycle or heterocycle bicycle or r3d and r8310s are used together with carbide to form cycle allowance； in this case, the above alternatives can be replaced by 0, 1, 2 or 3r1m3；a. Each r83100s, calculated independently, is hydrogen, tar, acylquine, asphalt, asphalt, cyclopentyl, isobutylene, oxygen, amide, aminobenzene, acid, hydrazine, sulfur, sulfur, sulfur, sulfonyl, cyanogen, isobutylene, arilo, hydroxy or nitro； r831222； e. Different tar
