PROBLEM TO BE SOLVED: To provide pharmaceutical compositions containing as an active ingredient a magnesium compound having an excellent effect in preventing or treating renal dysfunction caused by a platinum-containing chemistry formulation.SOLUTION: The present invention provides a pharmaceutical composition for preventing or treating renal dysfunction initiated by a platinum containing-chemical formulation, the pharmaceutical composition containing a magnesium compound as an active ingredient and being orally or parenterally administered to a patient to alleviate renal dysfunction caused by a platinum containing-chemical formulation and thereby being able to release the patient from disadvantages, such as renal failure and a temporal restriction of platinum compound excretion therapy to reduce the burden of a patient.SELECTED DRAWING: None【課題】白金含有化学製剤起因性腎障害に優れた予防効果または治療効果を有するマグネシウム化合物を有効成分とする、医薬組成物を提供すること。【解決手段】白金含有化学製剤により惹起される腎障害に対する予防または治療するための医薬組成物であって、その医薬組成物はマグネシウム化合物を有効成分とし、患者に経口的にもしくは非経口的に投与させることによって、白金化合物起因性腎障害を軽減させ、患者を白金化合物排泄療法の時間的拘束や腎不全などの不利益から解放でき患者の負担を軽減する医薬組成物。【選択図】なし