PROBLEM TO BE SOLVED: To provide pharmaceutical compositions containing as an active ingredient a magnesium compound having a preventive or therapeutic effect excellent in renal dysfunction caused by a platinum containing-chemical formulation, the compositions being characterized by using in combination with a platinum containing-chemical formulation for preventing or treating cancer.SOLUTION: The present invention provides a pharmaceutical composition for use in combination with a platinum containing-chemical formulation, the pharmaceutical composition containing a magnesium compound as an active ingredient and being orally or parenterally administered to a patient to alleviate renal dysfunction caused by a platinum containing-chemical formulation, thereby releasing the patient from disadvantages, such as renal failure and a temporal restriction of platinum compound excretion therapy.SELECTED DRAWING: None【課題】ガン予防または治療のための白金含有化学製剤を併用することを特徴とし、白金含有化学製剤起因性腎障害に優れた予防効果または治療効果を有するマグネシウム化合物を有効成分とする、医薬組成物を提供すること。【解決手段】白金含有化学製剤と併用する医薬組成物であって、その医薬組成物はマグネシウム化合物を有効成分とし、患者に経口的にもしくは非経口的に投与させることによって、白金化合物起因性腎障害を軽減させ、患者を白金化合物排泄療法の時間的拘束や腎不全などの不利益から解放でき患者の負担を軽減する医薬組成物。【選択図】なし
