Minoru Nakatsugawa,John Wayne Haller,Robert Andrew Davey,Rachel-Louise Kvertus Koktava,Kosuke Sakaue,Todd McNutt,Harry Quon,Scott Patrick Robertson,Zhi Cheng
申请号：
US15069688
公开号：
US09925393B2
申请日:
2016.03.14
申请国别(地区):
US
年份:
2018
代理人:
摘要：
An apparatus for determining a contour of a treatment region in a patient includes a computer processor to receive input regarding a contour of at least one organ-at-risk (OAR) adjacent to the treatment region receive input regarding an initial contour of the treatment region predict a radiation toxicity to the at least one OAR based on the contour of the at least one OAR, the initial contour of the treatment region, and a radiation treatment regimen determine whether the predicted radiation toxicity exceeds a threshold and determine a contour of the treatment region by iteratively modifying the initial contour of the treatment region, and any subsequent modified contours of the treatment region, until a stopping condition is satisfied. The stopping condition can be a preselected number of iterations or that the predicted radiation toxicity using the contour in place of the initial contour is first calculated is below said threshold.
