The invention provides non-irritating, stable topical compositions including at least Vitamin C, Vitamin E and a polyphenol antioxidant. Such compositions can be used to facilitate the prevention or treatment of free oxygen, nitrogen, and/or other free radical related skin damage. Also provided are methods for modifying free radical damage to skin by administering such compositions in an amount sufficient to treat and/or prevent free radical damage to the skin.本發明提供非刺激性、穩定之局部組成物，其至少包含維生素C、維生素E及多酚抗氧化劑。這類組成物可用於促進預防或治療與游離氧、氮及/或其他自由基相關之皮膚損害。本發明亦提供用於修改自由基對皮膚之損害的方法，該方法係經由投予足以治療及/或預防自由基對皮膚之損害之量的這類組成物來進行。
