A compound with the formula (1), characterized in that: R1 represents a hydrogen atom or a halogen atom； R2 represents an indanyl or tetralinyl group substituted or unsubstituted with one or more groups selected from halogen atoms, alkyl groups, hydroxy groups, alkoxy, amino, mono- or dialkylamino groups, carboxy groups, alkyloxycarbonyl groups, mono- or dialkylaminocarbonyl groups , carboxyamide, cyano, alkylsulfonyl and trifluoromethyl groups； R3 represents an aryl or heteroaryl group, substituted or unsubstituted with one or more atoms or groups selected from halogen atoms, alkyl groups, hydroxy groups, alkoxy, aralkyloxy groups, amino, mono- or dialkylamino groups, carboxy groups, alkyloxycarbonyl groups , mono- or dialkylaminocarbonyl groups, carboxyamide, cyano, alkylsulfonyl and trifluoromethyl groups； or a geometric isomer, tautomer, epimer, enantiomer, stereoisomer, diastereoisomer, racemate, salt or pharmaceutically acceptable solvate thereof, which is selected from the group consisting of: 2-chloro-4-hydroxy-3-indan-5-yl- 5-phenyl-7H-thieno [2,3-b] pyridin-6-one 2-chloro-5- (4-fluorophenyl) -4-hydroxy-3-indan-5-yl-7H-thieno [2,3 -b] pyridin-6-one 2-chloro-4-hydroxy-3-indan-5-yl-5- (3-methoxyphenyl) -7H-thieno [2,3-b] pyridin-6-one 2-chloro -4-hydroxy-3-indan-5-yl-5- (4-methoxyphenyl) -7H-thieno [2,3-b] pyridin-6-one 3- (2-chloro-4-hydroxy-3-indan -5-yl-6-oxo-7H-thieno [2,3-b] pyridin-5-yl-benzonitrile 2-chloro-4-hydroxy-3-indan-5-yl-5- (3-methylphenyl) - 7H-thieno [2,3-b] pyridin-6-one 2-chloro-5- (4-fluorophenyl) -4-hydroxy-3- (4-hydroxydan-5-yl) -7H-thieno [2,3 -b] pyridin-6-one 2-chloro-5- (3-fluorophenyl) -4-hydroxy-3- (4-hydroxydan-5-yl) -7H-thieno [2,3-b] pyridin-6- one 2-chloro-4-hydroxy-3-indan-5-yl-5- (3-pyridyl) -7H-thieno [2,3-b] pyridin-6-one 2-chloro-4-hydroxy-3- (4-hydroxydan-5-yl) -5-phenyl-7H-thieno [2,3-b] pyridin-6-one 2-cl gold-5- (2-fluorophenyl) -4-hydroxy-3- (4-hydroxydan-5-yl) -7H-thieno [2,3-b] pyridin-6-one 2-chloro-4-hydroxy-3 -
