Pyrimidone derivatives as tau protein kinase 1 inhibitors

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专利权人:

田辺三菱製薬株式会社

发明人:

酒井 大貴,中山 和樹,渡邉 和俊

申请号：

JP2013261020

公开号：

JP5688511B2

申请日:

2013.12.18

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

A pyrimidone derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof: wherein X represents hydrogen atom and Y represents hydroxyl group, or X represents fluorine atom and Y represents hydrogen atom； R1 represents a C1-6 alkyl group； R2 represents a morpholin-4-yl group which may be substituted, or the like, which is used for preventive and/or therapeutic treatment of a disease caused by tau protein kinase 1 hyperactivity such as a neurodegenerative diseases (e.g. Alzheimer disease).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/