THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人:
PETRUKHIN, KONSTANTIN,CIOFFI, CHRISTOPHER,JOHNSON, GRAHAM,DOBRI, NICOLETA,FREEMAN, EMILY,CHEN, PING,CONLON, MICHAEL,ZHU, LEI
申请号：
EP14769462
公开号：
EP2968304A4
申请日:
2014.03.13
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
The present invention provides a compound having the structure: (structurally represented) wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl R6 is H, OH, or halogen B is a substituted or unsubstituted heterobicycle, pyridazine, pyrazole, pyrazine, thiadiazole, or triazole, wherein the heterobicycle is other than chloro substituted indole and the pyrazole, when substituted, is substituted with other than trifluoromethyl, or a pharmaceutically acceptable salt thereof.
