The Trustees of Columbia University in the City of New York
发明人:
申请号：
EP18199124.1
公开号：
EP3495357A1
申请日:
2014.03.13
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The present invention provides a compound having the structure:whereinR1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl；R6 is H, OH, or halogen；B is a substituted or unsubstituted heterobicycle, pyridazine, pyrazole, pyrazine, thiadiazole, or triazole,wherein the heterobicycle is other than chloro substituted indole； andthe pyrazole, when substituted, is substituted with other than trifluoromethyl,or a pharmaceutically acceptable salt thereof.
