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Useful compounds for the treatment and / or care of the skin and its cosmetic or pharmaceutical compositions
专利权人:
Lubrizol Advanced Materials; Inc.
发明人:
FERRER MONTIEL, Antonio Vicente,ALMINANA DOMENECH, Núria,CEBRIAN PUCHE, Juan,VAN DEN NEST, Wim,CARRENO SERRAÏMA, Cristina,DELGADO GONZALEZ, Raquel
申请号:
ES14717794
公开号:
ES2639464T3
申请日:
2014.04.15
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
A compound of general formula (I): ** Formula ** its stereoisomers, mixtures thereof and / or their cosmetically or pharmaceutically acceptable salts, in which AA1 is selected from the group consisting of -Asp-, -Glu-, - Asn-, -Gln-, -Lys- and - Gly-; AA2 is selected from the group consisting of -Val-, -Leu-, -Ile-, -Met-, -Cit-, -His-, -Thr- and -GIn -; AA3 is selected from the group consisting of -Tyr-, -Trp- and 4-Abz; n is selected from the group consisting of 1, 2, 3 and 4. R3 is selected from the group consisting of H, or -AA2-AA1-R1. R1 is selected from the group consisting of H, a polymer derived from polyethylene glycol, substituted or unsubstituted aliphatic group, substituted or unsubstituted alicyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heteroaryl alkyl, substituted or unsubstituted aryl, substituted aralkyl or unsubstituted and R6-CO-, wherein R6 is selected from the group consisting of H, substituted or unsubstituted non-cyclic aliphatic group, substituted or unsubstituted alicyclyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, substituted heterocyclyl or unsubstituted and substituted or unsubstituted heteroarylalkyl; R2 is selected from the group consisting of -NR4R5, -OR4 and -SR4, in which R4 and R5 are independently selected from the group consisting of H, a polymer derived from polyethylene glycol, substituted or unsubstituted non-cyclic aliphatic group, substituted or unsubstituted alicyclyl substituted, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heteroarylalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted aralkyl; and R1 or R2 are not α-amino acids with the proviso that if R3 is H, then AA2 is selected from the group consisting of -Val-, -Leu-, -Ile- and -Met-, and AA1 is selected from the group formed by -Asp-, -Glu-, -Asn- and -GIn-.Un compuesto de fórmula general (I): **Fórmula** sus estereoisómeros, mezclas de los mismos y/o
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