HILINSKI, GERARD,SHIM, SO YOUN,PATTON, MATTHEW REISER,MCGEE, JOHN HANNEY,ORTET, PAULA,VERDINE, GREGORY L.
申请号：
CA3074838
公开号：
CA3074838A1
申请日:
2018.09.07
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Among other things, the present disclosure provides technologies for modulating functions of beta-catenin. In some embodiments, the present disclosure provides stapled peptides that interact with beta-catenin. In some embodiments, provided stapled peptides interact with beta-catenin at an Axin-binding site of beta-catenin. In some embodiments, the present disclosure provides compounds, compositions and methods for preventing and/or treating conditions, disorders and diseases that are associated with beta-catenin.
