HUESKEN, DIETER,BETTENCOURT, BRIAN,BUMCROT, DAVID,KUCHIMANCHI, SATYANARAYANA,MILSTEIN, STUART,SCHLABACH JR., MICHAEL,STEGMEIER, FRANK P.,WARMUTH, MARKUS,WEILER, JAN
申请号：
CA2860676
公开号：
CA2860676A1
申请日:
2013.01.08
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present disclosure relates to RNAi agents useful in methods of treating Beta-Catenin-related diseases such as adenomatous polyposis of the colon, colorectal cancer, basal cell carcinoma, breast cancer, kidney cancer, Wilms tumors, medulloblastoma, ovarian cancer, adrenocortical tumors, gastric cancer, liver cancer, melanoma, pancreatic cancers, prostate cancer, renal cancer, ectopic teeth and taste papillae, skin cancer, pilomatrixoma, anaplastic thyroid carcinoma, and uterine carcinosarcoma, oligodontia, osteoporosis, ageing, degenerative diseases, bedsores, chronic wounds and impaired wound healing, and similar and related diseases, using a therapeutically effective amount of a RNAi agent to Beta-Catenin.
