HILINSKI, Gerard,SHIM, So Youn,PATTON, Matthew,MCGEE, John,ORTET, Paula,VERDINE, Gregory
申请号：
SG11202001162T
公开号：
SG11202001162TA
申请日:
2018.09.07
申请国别(地区):
SG
年份:
2020
代理人:
摘要：
Among other things, the present disclosure provides technologies for modulating functions of beta-catenin. In some embodiments, the present disclosure provides stapled peptides that interact with beta-catenin. In some embodiments, provided stapled peptides interact with beta-catenin at an Axin-binding site of beta-catenin. In some embodiments, the present disclosure provides compounds, compositions and methods for preventing and/or treating conditions, disorders and diseases that are associated with beta-catenin.
