UTILISATION DE LA BETA-CATENINE EN TANT QUE BIOMARQUEUR POUR TRAITER DES CANCERS A L'AIDE D'UN ANTICORPS ANTI-DKK-1

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专利权人:

LEAP THERAPEUTICS; INC.

发明人:

KAGEY, MICHAEL H.,SIRARD, CYNTHIA A.

申请号：

CA3041325

公开号：

CA3041325A1

申请日:

2017.10.26

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

A method of treating a cancer in a subject in need thereof is disclosed. The cancer can be an esophageal cancer, a uterine cancer, a liver cancer, or a cholangiocarcinoma. The method comprises administering to the subject an effective amount of an anti-Dkk-1 antibody or antigen binding-fragment thereof, wherein the subject is determined to have a constitutively activating mutation of the beta-catenin protein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/