[problem], which provides, has excellent blood compatibility and therefrom the hollow-fiber membrane module of a dry type of one component of less release, builds up the hollow-fiber film of component, and the method for generating hollow-fiber membrane module. [solution] hollow-fiber membrane module, with built-in hollow-fiber film comprising it is characterized in that meeting a hydrophobic polymer and a hydrophilic polymer containing group for following project. (a) hollow-fiber film has a 10 wt% or less water content relative to its weight(b) hydrophobic polymer does not include nitrogen, and the hydrophilic polymer containing group includes nitrogen, and hollow-fiber film has a nitrogen content of 0.05-0.4 wt%(c) content of the hydrophilic polymer containing group in the inner surface of each film is 20-45 wt%(d) 2 amount. Dissolve in 10 milliliters of last primer liquids of one kind be 00 x 10-3 mole/liters of water liquor potassic permanganate by material consumption for titrating. The m2 of 2 milliliters or less every membrane areas
