A pharmaceutical combination for sensitizing a subject to a cancer treatment comprises an amount of metformin and an amount of statin. The amount of metformin and the amount of statin together constitute an effective amount of the pharmaceutical combination. The statin is selected from a group consisting of atorvastatin, fluvastatin, lovastatin, pravastatin, rosuvastatin, and simvastatin. The cancer treatment is preferably a radiotherapy. The pharmaceutical combination may be included in a pharmaceutical composition. A method of treating cancer is also provided. The method comprises administering the pharmaceutical combination to a subject and delivering an effective dose of radiation to the subject.
