SCHLESINGER, JACOB, J.,JIN, XIA,ROSE, ROBERT, C.,BLOCK, OLIVIA, K., T.,RODRIGO, SHANAKA I., W., W.
申请号：
EP11830053
公开号：
EP2621525A4
申请日:
2011.10.03
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
The disclosure provides a tetravalent Dengue virus vaccine, and methods of inducing a immune response against a Flavivirus such as Dengue virus 1-4 using the vaccine. The disclosure also provides methods of making a vaccine by introducing into a host cell a transgene that encodes a protein comprising Dengue domain III polypeptides, or, by purified dill polypeptides specific for Dengue serotypes 1-4, Yellow Fever Virus, West Nile Virus, Japanese Encephalitis Virus, and Flaviviruses.
