Claire Y. H. Kinney,Eric Thomas Beck,Richard M. Kinney
申请号：
US12990322
公开号：
US08715689B2
申请日:
2009.04.27
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The disclosure provides chimeric West Nile/Dengue viruses comprising non-coding regions, non-structural proteins, and a C protein from a West Nile virus and prM and E proteins from a Dengue virus. Also disclosed are methods of using the chimeric viruses in diagnosis of Dengue viral infection, assessment of candidate Dengue virus vaccine efficacy, and production of Dengue prM and E proteins.
