Centers for Disease Control and Prevention;The Government of the United States of America As Represented by the Secretary of the Department of Health and Human Services
发明人:
Kinney, Claire Y. H.,Beck, Eric Thomas,Kinney, Richard M.
申请号：
AU2009241354
公开号：
AU2009241354B2
申请日:
2009.04.27
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The disclosure provides chimeric West Nile/Dengue viruses comprising non- coding regions, non-structural proteins, and a C protein from a West Nile virus and prM and E proteins from a Dengue virus. Also disclosed are methods of using the chimeric viruses in diagnosis of Dengue viral infection, assessment of candidate Dengue virus vaccine efficacy, and production of Dengue prM and E proteins.
