PROBLEM TO BE SOLVED: To provide a diagnosis support device for supporting accurate diagnosis of AD of a subject whose facility or data base is different from that of a control group that serves as a criterion for prediction.SOLUTION: A diagnosis support device 1 includes: subject strength acquisition means 11 for acquiring functional connection strength of a default mode network in the inner temporal lobe region of a subject； standardization means 12 for calculating a z value indicating a position in the control strength distribution of the subject strength for each voxel value of the inner temporal lobe region based on the average and standard deviation of functional connection strength of a default mode network in the inner temporal lobe region of a control group of non-Alzheimer's disease； and index calculation means 13 for calculating an index for predicting whether or not the subject has Alzheimer's disease based on the z value.SELECTED DRAWING: Figure 2【課題】予測の基準となる対照群と施設またはデータベースが異なる被験者のＡＤを正確に診断することを支援する診断支援装置を提供する。【解決手段】診断支援装置１は、被験者の内側側頭葉領域のデフォルトモードネットワークの機能的結合強度を取得する被験強度取得手段１１と、アルツハイマー病ではない対照群の内側側頭葉領域のデフォルトモードネットワークの機能的結合強度の平均および標準偏差に基づき、前記被験強度の、前記対照強度の分布における位置を示すｚ値を、前記内側側頭葉領域のボクセル毎に算出する標準化手段１２と、前記ｚ値に基づいて、前記被験者がアルツハイマー病であるか否かを予測するための指標を算出する指標算出手段１３と、を備える。【選択図】図２
