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MICRO-ORGANISME DE PRODUCTION D'OLIGOSACCHARIDE DE LAIT HUMAIN
专利权人:
OLIGOSCIENCE BIOTECHNOLOGY GMBH
发明人:
PERACHA, MAX,WEMHOFF, SABRINA,MEINHARDT, FRIEDHELM
申请号:
CA3071309
公开号:
CA3071309A1
申请日:
2018.08.01
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Human milk oligosaccharides (HMOs) may be used e.g. as functional ingredients in infant nutrition, medical nutrition, functional foods and animal feed. There is still a need of improved means of producing HMOs. The present invention provides genetically modified microorganisms for the improved production of HMOs and HMO production methods using the same. The microorganisms of the invention may have one or more yield-enhancing modifications, including an inducible lysis system, which allows for the easy extraction of intracellular and extracellular HMOs, lactose permease mutants, which may increase intracellular lactose levels, or chaperones, which may increase intracellular availability of key enzymes for the production of HMOs.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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