Embodiments of the present disclosure include medical devices, and related methods of use, and manufacture thereof. A medical device is disclosed having an inner member and an outer member. The inner member may have a sharp edge, and the outer member may have a window configured to receive tissue. The medical device may include a plurality of suction passageways, the plurality of suction passageways may extend through at least one or both the inner member and the outer member and may be located adjacent the window. In addition, the inner member may be configured to move relative to the outer member.