The present invention relates to a kind of platycodon root polysaccharides extracted from campanulaceae rhizome, the catabolite of the polysaccharide, and the application from the preparation method for the method and platycodon root polysaccharide catabolite for extracting platycodon root polysaccharide in campanulaceae rhizome and the platycodon root polysaccharide and its catabolite in the drug of the disease of preparation treatment antitumor cell angiogenesis. The structure of platycodon root polysaccharide of the invention is (1 → 4)-α-D- gala pyrans uronic acid glycan, between degree of polymerization Jie's what 15-100, corresponding molecular weight is 2.0~18.0kD, and specific rotation is [α] D19+125 ° of (c 0.05, H2O it), and by following structural formula indicates. The molecular weight ranges of the catabolite of the campanulaceae pectin polysaccharide Partial acid hydrolysis are 1.4~3.0kDa. The significant lumen nucleus formation for inhibiting human microvascular endothelial cell (mvec) (HMEC-1) of energy is proved through experiment in vitro, is expected to as new construction anti-tumor drug, by inhibiting new vessels generation to inhibit the growth of solid tumor. α-D-GalpA-(1[→4)-α-D-GalpA-(1]x→4)-α-D-GalpA.本發明涉及一種從桔梗根莖中提取的桔梗多糖，該多糖的降解産物，以及從桔梗根莖中提取桔梗多糖的方法和桔梗多糖降解産物的製備方法，以及該桔梗多糖及其降解産物在製備治療抗腫瘤細胞血管生成的疾病的藥物中的應用。本發明的桔梗多糖的結構爲(1→4)-α-D-半乳吡喃糖醛酸聚糖，聚合度介於15-100之間，對應的分子量爲2.0～18.0kD，其比旋度爲[α]D19+125°(c 0.05，H2O)，並由以下結構式表示。所述桔梗果膠多糖部分酸水解的降解産物的分子量範圍爲1.4～3.0kDa。經體外實驗證明能顯著抑制人微血管內皮細胞(HMEC-1)的管腔生成作用，有望作爲新結構抗腫瘤藥物，通過抑制新生血管生成進而抑制固體瘤的生長。α-D-GalpA-(1[→4)-α-D-GalpA-(1]x→4)-α-D-GalpA。
