KWON, Taek Kwan,YAN, Xue Wen,WANG, Zhao Zhen,KIM, Yong Il,PARK, Jae Hyun,WOO, Jong Soo
申请号：
EP14871056
公开号：
EP3082766A4
申请日:
2014.12.17
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present invention relates to a liquid formulation comprising a solubilizer and montelukast or pharmaceutically acceptable salt thereof in a solution state as an active ingredient, and a method for preparing same. The liquid formulation of the present invention allows montelukast or pharmaceutically acceptable salt thereof to be substantially dissolved and present in a solution state, thereby preventing decrease of dissolution over time and increasing its bioavailability. In addition, because the liquid formulation of the present invention shows superior stability, taste and flavor, its medication compliance can be enhanced, and it can be effectively utilized for asthma and allergic rhinitis patients.
