MUCI, ALEX,FINER, JEFFREY T.,LU, PU-PING,RUSSELL, ALAN JAMES,MORGAN, BRADLEY P.,MORGANS, DAVID J., JR.
申请号:
DK13151376
公开号:
DK2583970T3
申请日:
2007.08.01
申请国别(地区):
DK
年份:
2015
代理人:
摘要:
Provided are certain chemical entities, and methods of use to modulate skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of obesity, sarcopenia, wasting syndrome, frailty, cachexia, muscle spasm, post-surgical and post-traumatic muscle weakness, neuromuscular disease, and other indications.