MUCI ALEX,MUCI Alex,FINER JEFFREY T.,FINER Jeffrey T.,LU PU-PING,LU Pu-Ping,RUSSELL ALAN JAMES,RUSSELL Alan James,MORGAN BRADLEY P.,MORGAN Bradley P.,MORGANS DAVID J. JR.,MORGANS David J. Jr.
申请号:
SI200731363
公开号:
SI2069352T1
申请日:
2007.08.01
申请国别(地区):
SI
年份:
2013
代理人:
摘要:
Provided are certain chemical entities, and methods of use to modulate skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of obesity, sarcopenia, wasting syndrome, frailty, cachexia, muscle spasm, post-surgical and post-traumatic muscle weakness, neuromuscular disease, and other indications.