Alan James Russell;Alex Muci;Bradley P. Morgan;Jeffrey T. Finer;Pu-Ping Lu;David J. Morgans, Jr.
发明人:
Alex Muci,Jeffrey T. Finer,Pu-Ping Lu,Alan James Russell,Bradley P. Morgan,David J. Morgans, Jr.
申请号：
US12765820
公开号：
US08293761B2
申请日:
2010.04.22
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Provided are certain chemical entities, and methods of use to modulate skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of obesity, sarcopenia, wasting syndrome, frailty, cachexia, muscle spasm, post-surgical and post-traumatic muscle weakness, neuromuscular disease, and other indications.
