A method for preventing and/or treating hyperlipidemia and related diseases thereof of a subject, comprising administering a preventively and/or therapeutically effective amount of plasminogen to a subject prone to suffer or suffering hyperlipidemia, or suffering other diseases accompanied by hyperlipidemia. The present invention also relates to a medicine, pharmaceutical composition, product, and kit comprising plasminogen and used for preventing and/or treating hyperlipidemia and related diseases thereof of a subject.本發明涉及用於預防和/或治療受試者高脂血症及其相關病症的方法,包括給藥易患高脂血症、患有高脂血症或罹患其它疾病並伴有高脂血症的受試者預防和/或治療有效量的纖溶酶原。本發明還涉及用於用於預防和/或治療受試者高脂血症及其相關病症的包含纖溶酶原的藥物、藥物組合物、製品、試劑盒。