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Pyrazolealkanamide substituted thiophenes as AMPA potentiators
专利权人:
MSD Oss B.V.
发明人:
MaClean, John Kinnaird Ferguson,Gillen, Kevin James,Jamieson, Craig,Rankovic, Zoran,Moir, Elizabeth Margaret
申请号:
AU2007271469
公开号:
AU2007271469B2
申请日:
2007.07.02
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention relates to a heterocyclic derivative according to Formula (I) wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising said heterocyclic derivatives and to their use in therapy, for instance in the treatment or prevention of psychiatric diseases where an enhancement of synaptic responses mediated by AMPA receptors is required, including schizophrenia, depression and Alzheimer's disease.
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