The present invention relates to methods for inducing and/or enhancing apoptosis in pathogenic cells. In particular, the present invention relates to the use of GnRH II antagonists in combination with at least one further compound selected from the group of selective estrogen receptor modulators (SERM), Aromatase inhibitors, and glycolysis inhibitors or salts or solvates thereof for inducing and/or enhancing apoptosis of specific types of tumor cells, expressing the GnRH II receptor as well as to methods relating thereto.
