The present invention provides a wireless lighting system for surgical instrument, which comprises a surgical instrument, and the surgical instrument at least comprises an action portion, a handle portion and a connection portion connecting the action portion and the handle portion a radio frequency emitting system, and the radio frequency emitting system emits a radio frequency signal in a wireless manner a radio frequency receiving system, and the radio frequency receiving system comprises a receiver, a converter and a light emitting element, which are electrically connected with each other. The radio frequency receiving system may be connected to the connection portion of the surgical instrument. The irradiation direction of the light emitting element of the radio frequency receiving system is toward the surgical area beside the action portion of the surgical instrument, so as to effectively generate the lighting effect during the surgery. Moreover, the radio frequency emitting system may control whether the light emitting element of the radio frequency receiving system emits light or not, and the light emitting strength.