Compositions and methods for disinfesting rooms and objects through a mist are disclosed. The compositions generally include a bactericidic and/or parasiticidic substance, a poly-acid or hydrophilic sulfone, and optionally a cell membrane polarizing component. By using an organic poly-acid or hydrophilic sulfone in a composition containing the bactericidic and/or parasiticidic substance, such as hydrogen peroxide or akacid, for disinfecting rooms and objects through a mist of said composition, it is possible also to kill mycobacteria.