< Topic >The solid garenusu formulation in order makes the quick discharge of the active ingredient possible, to prescribe the said active ingredient to the eye And, quick and can control can discharge the said active ingredient, offer the insertion for solubility ophthalmology.Solutions Being, the solid garenusu formulation in order to prescribe the active ingredient to the eye, at least it includes the water solubility for ophthalmology of 1 kinds and the shape medicine of organism compatibility, furthermore in the conjunctiva pouch, the said active ingredient in order for it to be possible, to release and to separate and direct compression, dry compression, wet compression and compression of freeze drying ones, the said compression at temperature below the 45C is done here, although it prescribes to the above-mentioned solid garenusu formulation and the eye which feature that it is something which is obtained and by each method of freeze drying it has the size which is suited, it consists the above-mentioned garenusu formulationIt is done, insertion for ophthalmology.【課題】有効成分の迅速な放出を可能とする、該有効成分を目に投与するための、固体ガレヌス製剤;及び、該有効成分を、迅速かつ制御放出できる、可溶性眼科用インサートを提供すること。【解決手段】有効成分を目に投与するための、固体ガレヌス製剤であって、少なくとも1種の眼科用の水溶性かつ生体適合性の賦形剤を含み、しかも結膜嚢に、該有効成分を解放かつ遊離することができるように、直接的圧縮、乾式圧縮、湿式圧縮、凍結乾燥物の圧縮、ここで該圧縮は45℃以下の温度にて行われる、および凍結乾燥の何れかの方法により得られたものであることを特徴とする上記固体ガレヌス製剤および目に投与するのに適した寸法をもつ、上記ガレヌス製剤で構成される、眼科用のインサート。
