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POLYMERE ET FORME PHARMACEUTIQUE AVEC PROPRIETES DE LIBERATION PROLONGEE ET RESISTANCE A L'INFLUENCE DE L'ETHANOL
专利权人:
EVONIK OPERATIONS GMBH
发明人:
ENDRES, THOMAS,MEIER, CHRISTIAN,HERMES, FLORIAN,DEL ROSARIO FERRAND, JESSICA,JUNG, HERBERT,EURICH, THOMAS,SCHATTKA, JAN HENDRIK
申请号:
CA3075204
公开号:
CA3075204A1
申请日:
2018.09.04
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The invention is concerned with a polymer, polymerized from a monomer mixture comprising: (a) 70 to 95% by weight of 2-Ethylhexyl methacrylate (EHMA) and Ethyl methacrylate (EMA or 2-Ethylhexyl methacrylate (EHMA) and methyl methacrylate (MMA), (b) 2.5 to 25% by weight of one or more C2 to C6 hydroxy-alkylesters of acrylic acid or methacrylic acid, (c) 2.5 to 15% by weight of one or more C2 to C8 alkyl esters of acrylic acid or of methacrylic acid with a quaternary cationic group in the alkyl group. Disclosed is also the use of a polymer for preparing a dosage form with a sustained release profile and resistance against the influence of ethanol and the dosage form itself.
来源网站:
中国工程科技知识中心
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