Thomas Endres,Christian Meier,Florian Hermes,Jessica del Rosario Ferrand,Herbert Jung,Thomas Eurich,Jan Hendrik Schattka
申请号：
US16646466
公开号：
US20200289423A1
申请日:
2018.09.04
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A polymer is polymerized from a monomer mixture containing (a) 70 to 95% by weight of 2-ethylhexyl methacrylate (EHMA) and ethyl methacrylate (EMA) or 2-ethylhexyl methacrylate (EHMA) and methyl methacrylate (MMA), (b) 2.5 to 25% by weight of one or more C2 to C6 hydroxy-alkyl esters of acrylic acid or methacrylic acid, (c) 2.5 to 15% by weight of one or more C2 to C8 alkyl esters of acrylic acid or of methacrylic acid with a quaternary cationic group in the alkyl group. The polymer is useful for preparing a dosage form with a sustained release profile and resistance against the influence of ethanol.
