This invention is related to a technology of quantitative analysis for Dopamine images, particularly a technical method to measure the absolute uptake from SPECT or SPECT/CT Dopamine images, and the application to evaluate the Dopamine activity in brain. Steps to realize the method include step of decay correction, step of intra-scan patient motion, step of scatter correction, step of attenuation correction, step of resolution recovery, step of noise reduction, step of calculating quantitative index and step of evaluation of Dopamine activity in brain. Through this invention, it is applicable to generate absolutely quantitative Dopamine SPECT images and quantitative indexes. This invention resolves the difficulty of quantifying Dopamine activity in brain with SPECT and SPECT/CT imaging as the technical method can be utilized to evaluate the Dopamine activity in brain.本發明是關於一種核醫學心臟圖像的定量技術,特別是關於一種多針孔SPECT或SPECT/CT的動態圖像定量重建與心肌血流絕對定量測量的技術方法,以及該技術方法在心肌血流狀態評估方面的用途。具體實施步驟包括:核素物理衰變校正步驟、掃描中患者移動校正步驟、散射校正步驟、幾何扭曲校正步驟、數據截斷補償步驟、組織衰減校正步驟、雜訊去除步驟、像素值轉換步驟、心肌血流定量計算步驟、血流狀態評估步驟。經本發明中的技術手段,可產生定量的多針孔動態SPECT心臟圖像,並可通過定量的多針孔動態圖像進行心肌血流絕對定量的計算,從而對心肌血流進行定量測量,同時以靜息血流、負荷血流與血流儲備等三項指標建立血流狀態圖,並實際應用於評估心肌血流的狀態,解決了利用多針孔SPECT和SPECT/CT動態顯像進行心肌血流定量測量的難題,並能夠使該技術方法用於心肌血流狀態的評估。
