This invention is related to a technique of SPECT image quantitation in nuclear medicine, particularly the measurement of bone standardized uptake value (SUV), lean SUV (SUL) and metabolic volume, and the application of this technique in evaluation of bone function. The practical steps include imaging acquisition, isotope decay correction, scatter correction, motion correction, attenuation correction, resolution recovery and noise reduction. Through this invention, it warrants to produce quantitative indexes from bone SPECT imaging that resolves the challenging issue of image quantitation with bone SPECT and SPECT/CT.本發明是關於一種骨圖像的定量檢測技術,特別是關於一種SPECT或SPECT/CT定量測量骨標準攝取值、瘦體標準攝取值和代謝體積的技術方法,以及此技術方法在骨評估方面的用途。實施步驟包括:圖像採集步驟、核素物理衰變校正步驟、散射校正步驟、移動校正步驟、組織衰減校正步驟、圖像空間解析度恢復步驟、雜訊去除步驟、骨代謝體積計算步驟、標準攝取值計算步驟和評估步驟。經本發明中的技術手段,可產生SPECT骨圖像的定量指標,解決了利用SPECT和SPECT/CT顯像進行骨定量分析的難題,並能夠使該技術用於骨的評估。
