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TOOLS AND METHODS FOR USING CELL DIVISION LOCI TO CONTROL PROLIFERATION OF CELLS
专利权人:
Sinai Health System
发明人:
NAGY Andras,MONETTI Claudio,LIANG Qin
申请号:
US201615556146
公开号:
US2018044686(A1)
申请日:
2016.03.09
申请国别(地区):
美国
年份:
2018
代理人:
摘要:
The present disclosure provides molecular tools, methods and kits for using cell division loci (CDLs) to control cell proliferation in animal cells. CDLs, as provided herein, are loci whose transcription product(s) are expressed during cell division. CDLs may be genetically modified, as described herein, to comprise a negative selectable marker and/or an inducible activator-based gene expression system, which allows a user to permit, ablate, and/or inhibit proliferation of the genetically modified cell(s) by adding or removing an appropriate inducer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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