Friedrich Blackkolb,Bernd Becker,Martha Reith,Manfred Isenberg,Anne Katrin Hilbert
申请号：
US13673978
公开号：
US09040058B2
申请日:
2012.11.09
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to a fermentation medium for cultivating Corynebacterium diphtheriae. The present invention also relates to the use of the fermentation medium in processes for obtaining diphtheria toxin from the Corynebacterium diphtheriae bacteria being cultivated and the preparation of vaccines using the diphtheria toxin obtained in the processes. The present invention further relates to a purification and detoxification processes specifically adapted for preparing a diphtheria toxoid for inclusion into a vaccine.
