Iverson Brent,Georgiou George,Taft Joseph M.,Yi Li
申请号:
US201414576766
公开号:
US9546359(B2)
申请日:
2014.12.19
申请国别(地区):
美国
年份:
2017
代理人:
Parker Highlander PLLC
摘要:
Provided are methods for protein engineering, such as engineering proteases or kinases. The methods may utilize yeast display and/or ER sequestration of proteins or substrates. In some aspects, TEV proteases with altered substrate specificity, potency, and/or efficiency are provided.