“2-[4-(PYRAZOL-4-YLALKYL)PIPERAZIN-1-YL]-3-PHENYL PYRAZINES AND PYRIDINES AND 3-[4-(PYRAZOL-4-YLALKYL)PIPERAZIN-1-YL]-2-PHENYL PYRIDINES AS 5-HT7 RECEPTOR ANTAGONISTS”
VALENTINA O. BADESCU,ANNE MARIE CAMP,BARRY PETER CLARK,MICHAEL PHILIP COHEN,SANDRA ANN FILLA,PETER THADDEUS GALLAGHER,SARAH LYNNE HELLMAN,MICHAEL PHILIP MAZANETZ,MARTA MARIA PINEIRO-NUNEZ,JOHN MEHNERT
申请号:
IN1901/MUMNP/2009
公开号:
IN258086B
申请日:
2009.10.14
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
The present invention provides selective 5-HT7 receptor antagonist compounds of Formula I and their use in the treatment of migraine, persistent pain, and anxiety: where A and B are each independently C(H)= or N=, provided that at least one of A and B is -N=, n is 1-3, m is 0-3, and R14 are as defined herein.