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Novel dihydronaphthalene compound and use thereof
专利权人:
发明人:
申请号:
EP08830489.4
公开号:
EP2192108B1
申请日:
2008.09.11
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Disclosed is a compound represented by the formula (I) below as a dihydronaphthalene compound having a chemical structure which is excellent in production efficiency when compared with lasofoxifene and nafoxidine. This compound is useful as a proteasome inhibitor and/or an antitumor agent. (In the formula, two -(CH 2 ) 1 -N(R 1 )(R 2 ) groups represent a same substituent R 1 and R 2 each represents a hydrogen atom, or a same or different alkyl group or alternatively, R 1 and R 2 may combine together to form a monocyclic heterocyclic ring with a nitrogen atom having them or additionally together with one or more atoms selected from an oxygen atom, a sulfur atom and a nitrogen atom R 3 , R 4 and R S each represents one or more substituents selected from a hydrogen atom, an alkyl group, an acyl group, an alicyclic group, an aromatic group, a halogen atom, an acyloxy group, a cyano group and a nitro group 1 represents an integer of 2-5 n represents an integer of 1-4 m represents an integer of 1-5 and q represents an integer of 1-3.)
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