A kinds of immunity regulatory composition that becomes for peptidoglycan of Lactobacillus and β-glucan of fungus using in immunotherapy. There are three structure that including nuclear structure、immunity regulatory composition and outside a function coat.本發明提供一種應用於減敏療法之免疫調節製劑組合物,為乳酸菌株胜肽多醣體與食/藥用真菌葡聚多醣體組合而成;免疫調節製劑組合物之劑型結構為三層,中心核心結構並黏附一層免疫調節製劑組合物再外包一層外衣。